Research

Principal Investigator

National Natural Science Foundation of China (×1)

Open Funding Project of National Key Laboratory (×1)

Natural Science Basic Research Plan in Shaanxi Province of China (×1)

Xidian University Specially Funded Project for Interdisciplinary Exploration (×1)

Fundamental Research Funds for the Central Universities (×4)

Enterprise Collaborative Project (×1)

Participated

National Natural Science Foundation of China (×5)

Selected Publications

[1] Yun Zeng, Taotao Dou, Lei Ma, and Jingwen Ma*. Biomedical photoacoustic imaging for molecular detection and disease diagnosis: “always-on” and “turn-on” probes. Advanced Science, 2022, 9(25), 2202384. 

[2] Yun Zeng*, Rachel L. Nixon, Wenyan Liu, and Risheng Wang*. The applications of functionalized DNA nanostructures in bioimaging and cancer therapy. Biomaterials, 2021, 268, 120560. 

[3] Yun Zeng, Huifang Liu, Jingwen Ma, Ke Li, Pang Chang, Chenying Wang, Lei Li, Dan Chen, Changhu Liu, Na Li*, Wenhua Zhan*, and Yonghua Zhan*. Cobalt ferrite-gossypol coordination nanoagents with high photothermal conversion efficiency sensitizing chemotherapy against Bcl-2 to induce tumor apoptosis. Small, 2023, 19(34), 2300104. 

[4] Yun Zeng, Yonghua Zhan*, Xinyue Liu, Jingwen Ma, Huifang Liu, Hanrui Li, Tong Yi, Qingxia Zhu, Getao Du, Linfei Zhao, Dan Chen, and Xueli Chen*. Highly efficient chemo/photothermal therapy alleviating tumor hypoxia against cancer and attenuate liver metastasis in vivo. Chemical Engineering Journal, 2022, 448, 137724. 

[5] Peng Chang, Yingying Guo, Dan Chen, Ke Li, Wei Wang, Zhihua Yang, Jingwen Ma*, Yun Zeng*, Wenhua Zhan*, Yonghua Zhan*. High-temperature PTT/CDT coordination nanoplatform realizing exacerbated hypoxia for enhancing hypoxia-activated chemotherapy to overcome tumor drug resistance. Journal of Nanobiotechnology, 2024, 22, 374. 

[6] Peng Chang, Jingwen Ma, Ke Li, Wei Wang, Dan Chen, Zhe Liu, Wenhua Zhan*, Yun Zeng*, and Yonghua Zhan*. 5-Hydroxytryptophan artificial synaptic vesicles across the blood-brain barrier for the rapid-acting treatment of depressive disorder. Materials Today Bio, 2024, 29, 101357.

[7] Yun Zeng, Linfei Zhao, Ke Li, Jingwen Ma, Dan Chen, Changhu Liu, Wenhua Zhan*, and Yonghua Zhan*. Aptamer-functionalized nanoplatforms overcoming temozolomide resistance in synergistic chemo/photothermal therapy through alleviating tumor hypoxia. Nano Research, 2023, 16(7), 9859-9872. 

[8] Yun Zeng, Peng Chang, Jingwen Ma, Ke Li, Chunhong Zhang, Yingying Guo, Hanrui Li, Qingxia Zhu, Huifang Liu, Wenjing Wang, Yuwei Chen, Dan Chen, Xu Cao*, and Yonghua Zhan*. DNA origami-anthraquinone hybrid nanostructures for in vivo quantitative monitoring of the progression of tumor hypoxia affected by chemotherapy. ACS Applied Materials & Interfaces, 2022, 14(5), 6387-6403. 

[9] Jingwen Ma*, Na Li, Jingjian Wang, Zhe Liu, Yulong Han, and Yun Zeng*. In vivo synergistic tumor therapies based on copper sulfide photothermal therapeutic nanoplatforms. Exploration, 2023, 3(5), 20220161. 

[10] Yun Zeng, Tong Yi, Jingwen Ma, Ming Han, Xinyi Xu, Dan Chen, Xueli Chen, Risheng Wang, and Yonghua Zhan*. Precisely controlled polydopamine-mediated antibacterial system: mathematical model of polymerization, prediction of antibacterial capacity, and promotion of wound healing. Nanotechnology, 2022, 33(45), 455102. 

Daocheng Wu, Jingwen Ma, Youshen Wu, Yun Zeng, Shihong Shen. CN 201510777717.1

Daocheng Wu, Ke Li, Jiajun Liu, Hao Liu, Yun Zeng. CN 201410668713.5

(1) Chinese Biomaterials Congress: 2023 (Chongqing), 2020 (Youth Forum, Beijing), 2019 (Dalian), 

2017 (Nanchang), 2015 (Haikou) 

(2) Chinese Society of Biomedical Engineering Conference & Medical Innovation Summit: 2024 (Shenzhen), 

2023 (Suzhou);  2019 (Youth Forum, Dalian)

(3) Chinese Biophysics Conference: 2024 (Lanzhou)

(4) Biophysics Society of China (nanobiology) & Chinese Society of Biomaterials (nanobiomaterials) 

Annual Meeting: 2024 (Sanya)

(5) Chinese Chemical Society: 2019 (National Polymer Academic Paper Conference, Xi'an)

(6) International Symposium on Molecular Imaging (ISMI): 2019 (Zhuhai)

(7) Symposium on Innovative Polymers for Controlled Delivery (SIPCD): 2018 (5th, Suzhou)

(8) Ozark Biomedical Initiative Research Symposium (OBIRS): 2017 (Rolla, USA)

Dr. Jingwen Ma, Ninth Hospital of Xi'an